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Research Articles & Reviews

Examining Blood Sample

Our papers mostly include molecular/cellular mechanisms of neurodegenerative diseases and roles of regulatory RNAs in this category.

International Publications in Peer-Reviewed Journals 

Yulug B, Uygur B, Sayman D, Akturk A, Cankaya S, Ayyıldız B,  Ayyıldız S, Salar AB, Ozansoy M, Hanoglu L, Altay O, Velioglu HA , Mardinoglu A, “The Role of Willpower in Major Depressive Disorder: An fMRI Study”, SSRN, Preprints with the Lancet, doi: 10.2139/ssrn.4445188.


Ozansoy M, Mikati H, Velioglu VA, Yulug B, “Exosomes: A missing link between chronic systemic inflammation and Alzheimer's disease?”, Biomed Pharmacother  2023 Jan 13;159:114161. doi: 10.1016/j.biopha.2022.114161. Review


Sahin Z, Biltekin SN, Ozansoy M, Hemiş B, Ozansoy MB, Yurttaş L, Berk B, Demirayak Ş, “Synthesis and in vitro antitumor activities of novel thioamide substituted piperazinyl‐1, 2, 4‐triazines”, Journal of Heterocyclic Chemistry, 2022, 59: 1333-1340. doi: 10.1002/jhet.4470


Ilktac HY, Kiziltan G, Lanpir AD, Ozansoy M, Gunal MY, Ozmen ST, Keskin I, Ozdemir EM, Kilic U, “Combined therapy with probiotic VSL# 3 and Omega-3 fatty acids attenuates colonic injury and inflammation in chronic DNBS-induced colitis in mice”, Folia Biologica (Krakow), 2021, 69(3), pp:135-146. doi: 10.3409/fb_69-3.15


Ilktac HY, Kiziltan G, Ozansoy M, Kilic U, Ozmen ST, Keskin I, Ozdemir EM, Gunal MY, “The effect of probiotic and omega-3 supplements on total oxidant and total antioxidant levels in experimental colitis”, Clinical and Experimental Health Sciences, 2021, 11(2), pp: 362-366.                              doi: 10.33808/clinexphealthsci.865058.


Avnioglu S, Ozansoy M, Cankaya S, Yildiz K, Hanoglu T, Polat B, Hanoglu L, “Empathy and Telepathy-Functional Imaging Psychiatric and Philosophic Correlates”, Biomedical Journal of Scientific & Technical Research, 2021, 38(5), pp: 30718-30720. doi: 10.26717/BJSTR.2021.38.006209


Ozansoy M, Altıntaş MÖ, Ozansoy MB, Günay N, Kılıç E, Kılıç Ü, “Two boron-containing compounds affect the cellular viability of SH-SY5Y cells in an in vitro amyloid-beta toxicity model”, Turkish Journal of Biology, 2020, doi: 10.3906/biy-2001-22


Ozansoy M, Ozansoy MB, Yulug B, Cankaya S, Kilic E, Goktekin S, Kilic U, “Melatonin Affects the Release of Exosomes and Tau-Content in In Vitro Amyloid-Beta Toxicity Model”, J Clin Neurosci, 2020, 73: 237-244, doi: 10.1016/j.jocn.2019.11.046


Yulug B, Saatci O, Isiklar A, Kilic U, Hanoglu L, Ozansoy M, Cankaya S, Cankaya B, Kilic E, “The association between HbA1c levels, olfactory memory and cognition in normal, pre-diabetic and diabetic persons” Endocr Metab Immune Disord Drug Targets. 2020 20(2): 198-212, doi: 10.2174/1871530319666190614121738


Günal MY, Yuluğ B, Çağlayan B, Ozansoy M, Kilic U, Keskin I, Kilic E, “A different view on the platelet aggregation inhibitor clopidogrel-a well-suitable anti-oedema agent in a preclinical model of brain injury”, Cesk Slov Neurol N 2019, 82: 115/5, 526-532. doi: 10.14735/amcsnn2019526


Şakul AA, Ozansoy M, Elibol B, Ayla Ş, Günal MY, Yozgat Y, Başağa SH, Şahin K, Kazancıoğlu R, Kılıç Ü, “Squalene Activates AKT/mTOR Pathway Against Cisplatin-Induced Kidney Damage”, Turkish Journal of Biology2019 43: 179-188. doi:10.3906/biy-1902-77. Equally contributed author


Yulug B, Ozansoy M, Cankaya S, Hanoglu L, Kilic U, Kilic E, “A Different View on the Pathophysiology of Parkinson’s Disease: A Descendent Neurochemical Hypothesis?” Neural Regen Res. 2019 Oct; 14(10): 1717-1718. doi: 10.4103/1673-5374.257527. Equally contributed author


Yuluğ B, Ozansoy M, Alökten M, Çetin-Ozansoy MB, Çankaya Ş, Hanoğlu L, Kılıç Ü, Kılıç E. “Minocycline increases in vitro cortical neuronal cell survival after laser axotomy”. Curr Clin Pharmacol. Feb 25, 2019. doi: 10.2174/1574884714666190226093119 Equally contributed author


Ceylan B, Ozansoy M, Kılıç Ü, Yozgat Y, Ercan Ç, Yıldız P, Aslan T, “N-acetylcysteine suppresses colistimethate sodium-induced nephrotoxicity via activation of SOD2, eNOS, and MMP3 protein expressions”, Renal Failure, Vol:40(1), pp:423-434, 2018. 


Mazi AR, Arzuman AS, Gurel B, Sahin B, Tuzuner MB, Ozansoy M, Baykal AT, “Neonatal Neurodegeneration in Alzheimer’s Disease Transgenic Mouse Model”, Journal of Alzheimer’s Disease Reports, Vol:2(1), pp: 79-91, 2018.


Gurel B, Cansev M, Sevinc C, Kelestemur S, Ocalan B, Cakir A, Aydin S, Kahveci N, Ozansoy M, Taskapilioglu O, Ulus IH, Başar MK, Sahin B, Tuzuner MB, Baykal AT, “Early Stage Alterations in CA1 Extracellular Region Proteins Indicate Dysregulation of IL6 and Iron Homeostasis in the 5XFAD Alzheimer’s Disease Mouse Model”, J. Alzheimers Dis., Vol: 61(4), pp:1399-1410, 2018.


Yulug B, Hanoglu L, Ozansoy M, Isik D, Kilic U, Kilic E, Schabitz WR, “The Therapeutic Role of Rifampicin in Alzheimer’s Disease”, Psychiatry Clin. Neurosci. Jan. 8, 2018. Review.


Keskin I, Günal MY, Aytürk N, Kilic U, Ozansoy M, Kilic E, "Dose-dependent Neuroprotective Effect of Enoxaparin on Cold-Induced Traumatic Brain Injury", Neural Regen Res, 12(5), pp: 761-764, 2017.


V Karatay, Y Denizhan, M Ozansoy, “Semiosis as Individuation: Integration of Multiple Orders of Magnitude”, Biosemiotics, October, pp:1-17, 2016.


AH Yamac, S Kucukbuzcu, M Ozansoy, O Gok, K Oz, M Erturk, E Yilmaz, B Ersoy, R Zeybek, O Goktekin, U Kilic, “Altered expression of micro-RNA 199a and increased levels of cardiac SIRT1 protein are associated with the occurrence of atrial fibrillation after coronary artery bypass graft surgery”, Cardiovascular Pathology, 25(3): 232-236, 2016.


M. Ozansoy, A.N. Başak, “The Central Theme of Parkinson’s Disease: α-Synuclein”, Molecular Neurobiology, 47(2): 460-465, 2013. Review


G. Cobanoglu, M. Ozansoy, A. N. Başak, “Are Alsin and Spartin Novel Interaction Partners?”, Biochemical and Biophysical Research Communications (BBRC), 427(1): 1-4, 2012.


I. Enunlu, M. Ozansoy, A. N. Başak, “Alfa-Class Prefoldin Protein UXT is a novel Interacting Partner of  Amyotrophic Lateral Sclerosis 2 (Als2) Protein”, Biochemical and Biophysical Research Communications (BBRC), 413(3); pp:471-475, September 30, 2011.


M. Ozansoy, Y. Denizhan, “The Endomembrane System: A Representation of the Extracellular Medium?”, Biosemiotics, Vol. 2, No: 3, pp: 255-267, 2009.


H.A. Hanagasi‌, P. Serdaroglu‌, M. Ozansoy‌, N. Basak‌, H. Tasli‌, M. Emre‌, “Mitochondrial Pathology in Muscle of a Patient with a Novel Parkin Mutation”, International Journal of Neuroscience, Vol. 119, No:10, pp: 1572-1583, 2009. 


M. Ozansoy, A. N. Başak, “Tauopathies: A Distinct Class of Neurodegenerative Diseases”, Balkan Journal of Medical Genetics, Vol. 10 No: 2, pp: 3-14, 2007. Review


M. Ozansoy, A.N. Başak, “Is Cell Death in Parkinson’s Disease Really Apoptosis?”, Balkan Journal of Medical Genetics,Vol. 9, No:1&2, pp:3-7, 2006. Review


HR Morris, R Katzenschlager, JC Janssen, JM Brown, M Ozansoy, N Quinn, T Revesz, MN Rossor, SE Daniel, NW Wood, AJ Lees. “Sequence Analysis of Tau in Familial and Sporadic Progressive Supranuclear Palsy”, Journal of Neurology, Neurosurgery and Psychiatry, 72:  388-390, 2002.


HR Morris MRCP, NL Khan BSc, JC Janssen MRCP, J Brown MD, J Perez-Tur PhD, M Baker BSc, M Ozansoy MSc, J Hardy PhD, M Hutton PhD, NW Wood PhD, AJ Lees MD, T Revesz MD, P Lantos MD, MN Rossor MD. “The Genetic and Pathological Classification of Familial Frontotemporal Dementia”, Archives of Neurology, Vol: 58, pp: 1813-1816 Nov 2001.

National Publications in Peer-Reviewed Journals

M Ozansoy, E Coşkun, MBÇ Ozansoy, Ş Çankaya, MY Günal, Z Bayraktaroğlu, B Yuluğ, L Hanoğlu, “The effect of rifampicin on the neuronal cell survival in primary cortical neuron culture after laser axotomy”, Acta Medica Alanya, 2019; 3(2): 135-140. doi: 10.30565/medalanya.553846


M Ozansoy, MB Çetin Ozansoy, “Changes in Als2 Expression Leads to Different Outcomes on the Expression of Two NF-kB Targeted Genes in N2a and C2C12 Cell Lines”, Med Med J 2019; 34: 123-129. doi:10.5222/MMJ.2019.05945.


Günal MY, Ozansoy M, Kılıç Ü, Keskin İ, Özdemir EM, Aslan İ, Eren Z, Ersavaş C, Kılıç E, “Role of erythropoietin and its receptor in the development of endometriosis in rats”, J  Turk Ger Gynecol Assoc, 20(1); pp:41-46, 2019.


MB Cetin Ozansoy, M Ozansoy, “Als2 Silencing Affects the Expression of Two NF-κB Targeted Genes via UXT in Adult Mouse Primary Spinal Motor Neuron Culture”, Med Med J, Vol:33, No:3, pp:227-234, 2018.


M. Ozansoy, A. N. Başak, “Tauopathies: A Distinct Class of Neurodegenerative Diseases”, Turkish Journal of Neurology (Turkish), Vol. 13, No: 1, pp: 1-29, 2007. Review


M. Ozansoy, A.N. Başak, “Programmed Cell Death in Parkinson’s Disease”, Journal of Parkinson’s Disease and Movement Disorders (Turkish), Vol: 9, No: 1, pp: 54-61, 2006. Review

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